An enhancer sequence from bovine papilloma virus DNA consists of two essential regions

An enhancer sequence from bovine papilloma virus DNA consists of two essential regions.

A comprehensive structural analysis of an enhancer sequence from bovine papilloma virus DNA is presented based on the construction and functional analysis of 20 mutant derivatives. The results, obtained in CV-1 tissue culture cells, show that this enhancer is a small genetic element--only 40 bp in length--that contains two essential regions. The two regions exhibit homology to each other and to...

Intracranial fibroblastic neoplasms in the hamster from bovine papilloma virus.

Intracranial Fibroblastic neoplasms developed in 16 of 19 hamsters inoculated intracerebrally with bovine papilloma virus. The tumors presumably arose in the meninges and infiltrated the adjacent brain along the vascular channels. Tumor nodules that developed in the subcutis of the extremities, ears, and body were probably due to viremia following intracerebral inoculation. Fibroblasts of the c...

Papilloma-like virus from bovine urinary bladder tumors.

Precipitin Response of Cattle to Bovine Papilloma Virus 1

Precipitins for bovine papilloma virus (BPV) which developed following experimental infection of 21 calves were character ized by diethylaminoethyl-cellulose chromatography, gel filtration with Sephadex G-200, sucrose density gradient, and ana lytic ultracentrifugation. A 19 S antibody alone was found 1 week after initial exposure to BPV which persisted at demon strable levels for 8 weeks. Both...

Precipitin response of cattle to bovine papilloma virus.

Precipitins for bovine papilloma virus (BPV) which developed following experimental infection of 21 calves were character ized by diethylaminoethyl-cellulose chromatography, gel filtration with Sephadex G-200, sucrose density gradient, and ana lytic ultracentrifugation. A 19 S antibody alone was found 1 week after initial exposure to BPV which persisted at demon strable levels for 8 weeks. Both...